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Nanoparticles Based on Silver Chloride and Bambusuril[6] for the Fine-Tuning of Biological Activity

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dc.contributor.author Turebayeva, Pana
dc.contributor.author Luchsheva, Venera
dc.contributor.author Fedorishin, Dmitriy
dc.contributor.author Yerkassov, Rakhmetulla
dc.contributor.author Bakibaev, Abdigali
dc.contributor.author Bolysbekova, Saltanat
dc.contributor.author Tugambayeva, Tokzhan
dc.contributor.author Sergazina, Samal
dc.contributor.author Nurmukhanbetova, Nurgul
dc.date.accessioned 2024-09-12T05:37:30Z
dc.date.available 2024-09-12T05:37:30Z
dc.date.issued 2023-11
dc.identifier.citation Turebayeva, P.; Luchsheva, V.; Fedorishin, D.; Yerkassov, R.; Bakibaev, A.; Bolysbekova, S.; Tugambayeva, T.; Sergazina, S.; Nurmukhanbetova, N. Nanoparticles Based on Silver Chloride and Bambusuril[6] for the Fine-Tuning of Biological Activity. Int. J. Mol. Sci. 2023, 24, 16126. https://doi.org/ 10.3390/ijms242216126 ru
dc.identifier.issn 1422-0067
dc.identifier.other doi.org/10.3390/ijms242216126
dc.identifier.uri http://rep.enu.kz/handle/enu/16234
dc.description.abstract The prevalence of numerous infectious diseases has emerged as a grave concern within the realm of healthcare. Currently, the issue of antibiotic resistance is compelling scientists to explore novel treatment approaches. To combat these infectious diseases, various treatment methods have been developed, harnessing cutting-edge disinfecting nanomaterials. Among the range of metallic nanoparticles employed in medicine, silver nanoparticles (AgNPs) stand out as both highly popular and well-suited for the task. They find extensive utility in cancer diagnosis and therapies and as effective antibacterial agents. The interaction between silver and bacterial cells induces significant structural and morphological alterations, ultimately leading to cell demise. In this study, nanoparticles based on silver and bambusuril[6] (BU[6]) were developed for the first time. These NPs can be used for different biomedical purposes. A simple, single-step, and effective synthesis method was employed to produce bambusuril[6]-protected silver chloride nanoparticles (BU[6]-Ag/AgCl NPs) through the complexation of BU[6] with silver nitrate. The NPs were characterized using X-ray phase analysis (XPS), infrared spectroscopy (IR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). When the SEM images were examined, it was seen that the synthesized BU[6]-Ag/AgCl NPs were distributed with homogeneous sizes, and the synthesized NPs were mostly spherical and cubic. The EDS spectra of BU[6]-Ag/AgCl NPs demonstrated the presence of Ag, Cl, and all expected elements. BU[6]-Ag/AgCl NPs showed high antibacterial activity against both E. coli and S. aureus bacteria. ru
dc.language.iso en ru
dc.publisher International Journal of Molecular Sciences ru
dc.relation.ispartofseries Volume 24;Issue 22
dc.subject bambusuril ru
dc.subject silver chloride nanoparticles ru
dc.subject MTT-test ru
dc.subject thermal analysis ru
dc.subject supramolecular chemistry ru
dc.subject antibacterial activity ru
dc.title Nanoparticles Based on Silver Chloride and Bambusuril[6] for the Fine-Tuning of Biological Activity ru
dc.type Article ru


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