Abstract:
The prevalence of numerous infectious diseases has emerged as a grave concern within the
realm of healthcare. Currently, the issue of antibiotic resistance is compelling scientists to explore
novel treatment approaches. To combat these infectious diseases, various treatment methods have
been developed, harnessing cutting-edge disinfecting nanomaterials. Among the range of metallic
nanoparticles employed in medicine, silver nanoparticles (AgNPs) stand out as both highly popular
and well-suited for the task. They find extensive utility in cancer diagnosis and therapies and as
effective antibacterial agents. The interaction between silver and bacterial cells induces significant
structural and morphological alterations, ultimately leading to cell demise. In this study, nanoparticles
based on silver and bambusuril[6] (BU[6]) were developed for the first time. These NPs can be used for
different biomedical purposes. A simple, single-step, and effective synthesis method was employed
to produce bambusuril[6]-protected silver chloride nanoparticles (BU[6]-Ag/AgCl NPs) through the
complexation of BU[6] with silver nitrate. The NPs were characterized using X-ray phase analysis
(XPS), infrared spectroscopy (IR), thermogravimetric analysis (TGA), scanning electron microscopy
(SEM) and energy-dispersive X-ray spectroscopy (EDS). When the SEM images were examined, it
was seen that the synthesized BU[6]-Ag/AgCl NPs were distributed with homogeneous sizes, and
the synthesized NPs were mostly spherical and cubic. The EDS spectra of BU[6]-Ag/AgCl NPs
demonstrated the presence of Ag, Cl, and all expected elements. BU[6]-Ag/AgCl NPs showed high
antibacterial activity against both E. coli and S. aureus bacteria.
