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Biochemistry, Genetics and Molecul: Recent submissions

Now showing items 1-20 of 83

Rotational Barriers in N-Benzhydrylformamides: An NMR and DFT Study

Sadvakassova, Madina Zh.; Khlebnikov, Andrei I.; Bakibaev, Abdigali A.; Kotelnikov, Oleg A.; Erkassov, Rakhmetulla Sh.; Yelubay, Madeniyet A.; Issabayeva, Manar A. (Molecules, 2023)

N-Benzhydrylformamides are pharmacologically active compounds with anticonvulsant, enzyme-inducing, antihypoxic, and other types of biological activity. The conformational behavior of benzhydrylformamides is determined ...
Methods of Analysis and Identification of Betulin and Its Derivatives

Takibayeva, Altynaray T.; Zhumabayeva, Gulistan K.; Bakibaev, Abdigali A.; Demets, Olga V.; Lyapunova, Maria V.; Mamaeva, Elena A.; Yerkassov, Rakhmetulla Sh.; Kassenov, Rymchan Z.; Ibrayev, Marat K. (Molecules, 2023)

This scientific work presents practical and theoretical material on the methods of analysis and identification of betulin and its key derivatives. The properties of betulin and its derivatives, which are determined by ...
Low-Dose Radiation Exposure with 56MnO2 Powder Changes Gene Expressions in the Testes and the Prostate in Rats

Fujimoto, Nariaki; Amantayeva, Gaukhar; Chaizhunussova, Nailya; Shabdarbayeva, Dariya; Abishev, Zhaslan; Ruslanova, Bakhyt; Zhunussov, Yersin; Azhimkhanov, Almas; Zhumadilov, Kassym; Petukhov, Aleksey; Stepanenko, Valeriy; Hoshi, Masaharu (International Journal of Molecular Sciences, 2020)

To investigate the biological effects of internal exposure of radioactive 56MnO2 powder, the major radioisotope dust in the soil after atomic bomb explosions, on male reproductive function, the gene expression of the ...
Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp

Suleimen, Yerlan M.; Suleimen, Y.M.; Jose, Eslam B.; Elkaeed, E.B.; Eissa, Ibrahim H.; Eissa, I.H.; Metwaly, Ahmed M. (Molecules, 2022)

Two rare 2-phenoxychromone derivatives, 6-demethoxy-4‘-O-capillarsine (1) and tenuflorin C (2), were isolated from the areal parts of Artemisia commutata and A. glauca, respectively, for the first time. Being rare in ...
Investigating the Influence of Column Depth on the Treatment of Textile Wastewater Using Natural Zeolite

Mkilima, Timoth; Meiramkulova, Kulyash; Ubaidulayeva, Nurbala; Zandybay, Amanbek; Khusainov, Mansur; Nurmukhanbetova, Nurgul; Tastanova, Lyazzat; Mashan, Toghan; Meirbekov, Abdilda (Molecules, 2021)

Textile industry production processes generate one of the most highly polluted wastewaters in the world. Unfortunately, the field is also challenged by the availability of relatively cheap and highly effective technologies ...
EZ-SEP: Extended Z-SEP Routing Protocol with Hierarchical Clustering Approach for Wireless Heterogeneous Sensor Network

Nurlan, Zhanserik; Zhukabayeva, Tamara; Othman, Mohamed (Sensors (Switzerland), 2021)

Wireless sensor networks (WSN) are networks of thousands of nodes installed in a defined physical environment to sense and monitor its state condition. The viability of such a network is directly dependent and limited ...
Evaluation of the Efficiency of Detection and Capture of Manganese in Aqueous Solutions of FeCeOx Nanocomposites Doped with Nb2O5

Kozlovskiy, Artem; Egizbek, Kamila; Zdorovets, Maxim V.; Ibragimova, Milana; Shumskaya, Alena; Rogachev, Alexandr A.; Ignatovich, Zhanna V.; Kadyrzhanov, Kayrat (Sensors, 2020)

The main purpose of this work is to study the effectiveness of using FeCeOx nanocomposites doped with Nb2O5 for the purification of aqueous solutions from manganese. X-ray diffraction, energy–dispersive analysis, scanning ...
DJ-1 protects proteins from acylation by catalyzing the hydrolysis of highly reactive cyclic 3-phosphoglyceric anhydride

Akhmadi, Aizhan; Yeskendir, Adilkhan; Dey, Nelly; Mussakhmetov, Arman; Shatkenova, Zariat; Kulyyassov, Arman; Andreeva, Anna; Utepbergenov, Darkhan; Shatkenova, Zariat; Kulyyassov, Arman; Andreeva, Anna; Utepbergenov, Darkhan (Nature Communications, 2023)

Mutations in the human PARK7 gene that encodes protein DJ-1 lead to familial Parkinsonism due to loss of dopaminergic neurons. However, the molecular function of DJ-1 underpinning its cytoprotective effects are unclear. ...
Characterization of Activated Carbon from Rice Husk for Enhanced Energy Storage Devices

Unknown author (Molecules, 2023)

The production of activated carbon (AC) from lignocellulosic biomass through chemical activation is gaining global attention due to its scalability, economic viability, and environmental advantages. Chemical activation ...
Boron and Gadolinium Loaded Fe3O4 Nanocarriers for Potential Application in Neutron Capture Therapy

Korolkov, Ilya V.; Zibert, Alexandr V.; Lissovskaya, Lana I.; Ludzik, K.; Anisovich, M.; Kozlovskiy, Artem L.; Shumskaya, A. E.; Vasilyeva, M.; Shlimas, Dmitriy I.; Jazd, Monika; Marciniak, Beata; Kontek, Renata; Chudoba, Dorota; Zdorovets, Maxim V. (International Journal of Molecular Sciences, 2021)

In this article, a novel method of simultaneous carborane- and gadolinium-containing compounds as efficient agents for neutron capture therapy (NCT) delivery via magnetic nanocarriers is presented. The presence of both ...
Assessment of the Irradiation Exposure of PET Film with Swift Heavy Ions Using the Interference-Free Transmission UV-Vis Transmission Spectra

Tuleushev, Adil Z.; Harrison, Fiona E.; Kozlovskiy, Artem L.; Zdorovets, Maxim V. (Polymers, 2021)

This paper presents the results of a study of polyethylene terephthalate (PET) films irradiated with Ar and Kr ions at both normal orientation and an angle of 40◦ to the normal. Normal irradiation was performed using ...
Assessing the Influence of Electrode Polarity on the Treatment of Poultry Slaughterhouse Wastewater

Meiramkulova, Kulyash; Bazarbayeva, Tursynkul; Orynbassar, Raigul; Tleukulov, Almas; Madina, Nabiollina; Mashan, Togzhan; Akubayeva, Dariya; Apendina, Ainagul; Nurmukhanbetova, Nurgul (Molecules, 2022)

Electrochemical methods have been increasingly gaining popularity in the field of wastewater treatment. However, the performance of these methods can be highly affected by the polarity direction as determined by the ...
The Determination of the Biocompatibility of New Compositional Materials, including Carbamide-Containing Heterocycles of Anti-Adhesion Agents for Abdominal Surgery

Kanasheva, Nurdana; Fedorishin, Dmitry A.; Lyapunova, Maria V.; Bukterov, Mikhail V.; Kaidash, Olga A.; Bakibaev, Abdigali A.; Yerkassov, Rakhmetulla; Mashan, Togzhan; Nesmeyanova, Rimma; Ivanov, Vladimir V.; Udut, Elena V.; Tuguldurova, Vera P.; Salina, Margarita V.; Malkov, Victor S.; Knyazev, Alexey S. (Molecules, 2024)

Due to traumatic injuries, including those from surgical procedures, adhesions occur in over 50% of cases, necessitating exclusive surgical intervention for treatment. However, preventive measures can be implemented ...
Effect of pre-sowing treatment of soybean seeds with inoculant and microelements for yield and quality in the conditions of south-east of Kazakhstan

Kabylbekova, Gaukhar; Didorenko, Svetlana; Kassenov, Rinat; Dalibaeva, Almagul; Alikulov, Zerekbai (OCL - Oilseeds and fats, Crops and Lipids, 2024)

Soybean is a high-protein and at the same time an oilseed crop. Its cultivation brings profit from the sale of seeds and enriches the soil through the activity of nitrogen-fixing plants. The effectiveness of pre-sowing ...
Internal doses in experimental mice and rats following exposure to neutron‑activated 56MnO2 powder: results of an international, multicenter study

Stepanenko, Valeriy ; Kaprin, Andrey ; Ivanov, Sergey; Shegay, Peter ; Zhumadilov, Kassym ; Petukhov, Aleksey ; Kolyzhenkov, Timofey ; Bogacheva, Viktoria ; Zharova, Elena ; Iaskova, Elena; Chaizhunusova, Nailya ; Shabdarbayeva, Dariya ; Amantayeva, Gaukhar ; Baurzhan, Arailym ; Ruslanova, Bakhyt ; Abishev, Zhaslan ; Apbassova, Madina ; Kairkhanova, Ynkar ; Uzbekov, Darkhan ; Khismetova, Zaituna ; Zhunussov, Yersin ; Fujimoto, Nariaki ; Sato, Hitoshi ; Shichijo, Kazuko ; Nakashima, Masahiro ; Sakaguchi, Aya ; Toyoda, Shin ; Kawano, Noriyuki ; Ohtaki, Megu ; Otani, Keiko ; Endo, Satoru ; Yamamoto, Masayoshi ; Hoshi, Masaharu (Radiation and Environmental Biophysics, 2020-11)

The experiment was performed in support of a Japanese initiative to investigate the biological efects of irradiation from residual neutron-activated radioactivity that resulted from the A-bombing. Radionuclide 56Mn ...
Involvement of Circulating Cell-Free Mitochondrial DNA and Proinflammatory Cytokines in Pathogenesis of Chronic Obstructive Pulmonary Disease and Lung Cancer

Bulgakova, Olga; Kausbekova, Asemgul; Kussainova, Assiya; Kalibekov, Nurtas; Serikbaiuly, Dulat; Bersimbaev, Rakhmetkazhi (Asian Pacific Journal of Cancer Prevention, 2021-06)

Circulating cell-free mitochondrial DNA (cf-MtDNA) has been reported in patients with chronic obstructive pulmonary disease (COPD) and lung cancers. However, inter-relationships among the three biological events have ...
The Vitamin C Enantiomers Possess a Comparable Potency in the Induction of Oxidative Stress in Cancer Cells but Differ in Their Toxicity

Begimbetova, Dinara; Burska, Agata N.; Baltabekova, Aidana; Kussainova, Assiya; Kukanova, Assiya; Fazyl, Fatima; Ibragimova, Milana; Manekenova, Kenzhekyz; Makishev, Abay; Bersimbaev, Rakhmetkazhi I.; Sarbassov, Dos D. (International Journal of Molecular Sciences, 2024)

The use of vitamin C (VC) in high doses demonstrates a potent tumor suppressive effect by mediating a glucose-dependent oxidative stress in Kirsten rat sarcoma (KRAS) mutant cancer cells. VC with arsenic trioxide (ATO) ...
Radon Biomonitoring and microRNA in Lung Cancer

Bersimbaev, Rakhmet; Pulliero, Alessandra; Bulgakova, Olga; Kussainova, Assiya; Aripova, Akmara; Izzotti, Alberto (International Journal of Molecular Sciences, 2020)

Radon is the number one cause of lung cancer in non-smokers. microRNA expression in human bronchial epithelium cells is altered by radon, with particular reference to upregulation of miR-16, miR-15, miR-23, miR-19, ...
Whole-Genome Sequence-Based Characterization of Pre-XDR M. tuberculosis Clinical Isolates Collected in Kazakhstan

Daniyarov, Asset; Akhmetova, Ainur; Rakhimova, Saule; Abilova, Zhannur; Yerezhepov, Dauren; Chingissova, Lyailya; Bismilda, Venera; Takenov, Nurlan; Akilzhanova, Ainur; Kairov, Ulykbek; Kozhamkulov, Ulan (Diagnostics, 2023)

Background: Kazakhstan has a high burden of multidrug-resistant tuberculosis in the Central Asian region. This study aimed to perform genomic characterization of Mycobacterium tuberculosis strains obtained from Kazakhstani ...
The Role of Mitochondrial miRNAs in the Development of Radon-Induced Lung Cancer

Kussainova, Assiya; Bulgakova, Olga; Aripova, Akmaral; Khalid, Zumama; Bersimbaev, Rakhmetkazhi; Izzotti, Alberto (Biomedicines, 2022)

MicroRNAs are short, non-coding RNA molecules regulating gene expression by inhibiting the translation of messenger RNA (mRNA) or leading to degradation. The miRNAs are encoded in the nuclear genome and exported to the ...

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