Biochemistry, Genetics and Molecul: Recent submissions

  • Effects of Radioactive 56MnO2 Particle Inhalation on Mouse Lungs: A Comparison between C57BL and BALB/c 
    Abishev, Zhaslan; Ruslanova, Bakhyt; Apbassova, Saulesh; Shabdarbayeva, Dariya; Chaizhunussova, Nailya; Dyusupov, Altai; Azhimkhanov, Almas; Zhumadilov, Kassym; Stepanenko, Valeriy; Ivanov, Sergey; Shegay, Peter; Kaprin, Andrey; Hoshi, Masaharu; Fujimoto, Nariaki (International Journal of Molecular Sciences, 2023-12)
    The effects of residual radiation from atomic bombs have been considered to be minimal because of its low levels of external radioactivity. However, studies involving atomic bomb survivors exposed to only residual radiation ...
  • Effects of Internal Exposure of Radioactive 56MnO2 Particles on the Lung in C57BL Mice 
    Abishev, Zhaslan; Ruslanova, Bakhyt; Apbassova, Saulesh; Chaizhunussova, Nailya; Shabdarbayeva, Dariya; Azimkhanov, Almas; Zhumadilov, Kassym; Stepanenko, Valeriy; Ivanov, Sergey; Shegay, Peter; Hoshi, Masaharu; Fujimoto, Nariaki (Current Issues in Molecular Biology, 2023)
    The investigation of the radiation effects of the atomic bombing in Hiroshima and Nagasaki has revealed concerns about the impact of the residual radioactive dust produced in the soil. Manganese-56 is one of the major ...
  • Effect of Rh Doping on Optical Absorption and Oxygen Evolution Reaction Activity on BaTiO3 (001) Surfaces 
    Inerbaev, Talgat M.; Abuova, Aisulu U.; Zakiyeva, Zhadyra Ye.; Abuova, Fatima U.; Mastrikov, Yuri A.; Sokolov, Maksim; Gryaznov, Denis; Kotomin, Eugene A. (Molecules, 2024)
    In the present work, we investigate the potential of modified barium titanate (BaTiO3 ), an inexpensive perovskite oxide derived from earth-abundant precursors, for developing efficient water oxidation electrocatalysts ...
  • Diverse Biological Activity of Benzofuroxan/Sterically Hindered Phenols Hybrids 
    Chugunova, Elena; Gibadullina, Elmira; Matylitsky, Kirill; Bazarbayev, Baurat; Neganova, Margarita; Volcho, Konstantin; Rogachev, Artem; Akylbekov, Nurgali; Tran Nguyen, Hoang Bao; Voloshina, Alexandra; Lyubina, Anna; Amerhanova, Syumbelya; Syakaev, Victor; Burilov, Alexander; Appazov, Nurbol; Zhanakov, Mukhtar; Kuhn, Leah; Sinyashin, Oleg; Alabugin, Igor (Pharmaceuticals, 2023)
    Combining two pharmacophores in a molecule can lead to useful synergistic effects. Herein, we show hybrid systems that combine sterically hindered phenols with dinitrobenzofuroxan fragments exhibit a broad range of ...
  • Development of an Artificial Vision for a Parallel Manipulator Using Machine‑to‑Machine Technologies 
    Nussibaliyeva, Arailym; Sergazin, Gani; Tursunbayeva, Gulzhamal; Uzbekbayev, Arman; Zhetenbayev, Nursultan; Nurgizat, Yerkebulan; Bakhtiyar, Balzhan; Orazaliyeva, Sandugash; Yussupova, Saltanat (Sensors, 2024)
    This research focuses on developing an artificial vision system for a flexible delta robot ma‑ nipulator and integrating it with machine‑to‑machine (M2M) communication to optimize real‑time device interaction. This ...
  • Continuous Sign Language Recognition and Its Translation into Intonation-Colored Speech 
    Amangeldy, Nurzada; Ukenova, Aru; Bekmanova, Gulmira; Razakhova, Bibigul; Milosz, Marek; Kudubayeva, Saule (Sensors, 2023)
    This article is devoted to solving the problem of converting sign language into a consistent text with intonation markup for subsequent voice synthesis of sign phrases by speech with intonation. The paper proposes an ...
  • Comparative Analysis of Natural and Synthetic Zeolite Filter Performance in the Purification of Groundwater 
    Meiramkulova, Kulyash; Kydyrbekova, Aliya; Devrishov, Davud; Ubaidulayeva, Nurbala; Tuyakbayeva, Akmaral; Zhangazin, Sayan; Ualiyeva, Rimma; Kolpakova, Valentina; Yeremeyeva, Yuliya; Mkilima, Timoth (Water, 2023)
    Zeolite materials are among the relatively cheap and readily available materials for wastewater treatment. However, the performance of zeolite-based systems can be highly affected by the material properties. In this study, ...
  • Chargaff’s second parity rule lies at the origin of additive genetic interactions in quantitative traits to make omnigenic selection possible 
    Matkarimov, Bakhyt T.; Saparbaev, Murat K. (PeerJ, 2023)
    Background. Francis Crick’s central dogma provides a residue-by-residue mechanistic explanation of the flow of genetic information in living systems. However, this principle may not be sufficient for explaining how random ...
  • Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination with Anticancer Drugs on C6 Rat Glioma Model Cells 
    Mukusheva, Gulim K.; Jalmakhanbetova, Roza I.; Shaibek, Altynay Zh.; Nurmaganbetova, Manshuk S.; Zhasymbekova, Aigerym R.; Nurkenov, Oralgazy A.; Akishina, Ekaterina A.; Kolesnik, Irina A.; Dikusar, Evgenij A.; Terpinskaya, Tatiana I.; Kulchitsky, Vladimir A.; Potkin, Vladimir I.; Pushkarchuk, Alexander L.; Lyakhov, Dmitry A.; Michels, Dominik L. (Molecules, 2024)
    Alkaloid-based urea derivatives were produced with high yield through the reaction of anabasine and cytisine with isoxazolylphenylcarbamates in boiling benzene. Their antitumor activity, in combination with the commonly ...
  • Absorption of Water Vapor by Bambus[6]uril and a Density Functional Theory Study of Its Aqua Complexes 
    Turebayeva, Pana; Guslyakov, Alexey N.; Novikova, Svetlana A.; Khlebnikov, Andrei I.; Befus, Ekaterina A.; Meshcheryakov, Evgeniy P.; Bakibaev, Abdigali A.; Kusepova, Lyazat; Kassenova, Nazira; Sharipova, Sarzhan; Yerkassov, Rakhmetulla (Molecules, 2023)
    The absorption/desorption of water vapor by bambus[6]uril (Bu[6]) has been studied. According to kinetic experiments, the absorption capacity of Bu[6] is 4 moles of water per 1 mole of Bu[6] with the absorption duration ...
  • Method for assessing the content of molybdenum enzymes in the internal organs of fish 
    Satkanov, Mereke; Tazhibay, Diana; Zhumabekova, Bibigul; Assylbekova, Gulmira; Abdukarimov, Nurzhan; Nurbekova, Zhadyrassyn; Kulatayeva, Maral; Aubakirova, Karlygash; Alikulov, Zerekbai (MethodsX, 2024-01)
    Molybdenum enzymes (Mo-enzymes) contain a molybdenum cofactor (MoCo) in the active site. These enzymes are potentially interesting for studying the survival mechanism of fish under hypoxic water conditions. This is because ...
  • The cell cycle regulatory gene polymorphisms TP53 (rs1042522) and MDM2 (rs2279744) in lung cancer: a meta-analysis 
    Bulgakova, O.; Kussainova, A.; Bersimbaev, R. (Вавиловский журнал генетики и селекции, 2020)
    Lung cancer is one of the most common types of cancer in the world. Although the mechanism of lung cancer is still unknown, a large number of studies have found a link between gene polymorphisms and the risk of lung ...
  • Relationship between isokinetic strength of the knee joint and countermovement jump performance in elite boxers 
    Chen, Chao; Ali, Zhalel; Muhammad Abdul, Rehman Rashid; Marchibayeva, Ulbossyn Samethanovna; Guodong, Wu; Sagidolla, Mukhametkali; Tussipkan, Dilnur (PeerJ, 2023-12)
    Background. The lower limbs play a key role to develop the linear momentum for hitting power in effective boxing. The knee extensor and flexor strength guarantees the dynamic stability of boxers. The insufficient extensor ...
  • Purification and Properties of Polyphenol Oxidase of Dried Volvariella bombycina 
    Sarsenova, Assemgul; Demir, Dudu; Ça ˘glayan, Kardelen; Abiyev, Sardarbek; Darbayeva, Talshen; Eken, Cafer (Biology, 2023)
    Polyphenol oxidase (PPO) was purified and characterized from a dried wild edible and medicinal mushroom (V. bombycina). Using Sepharose 4B-L-tyrosine-p-aminobenzoic acid affinity chromatography, PPO was purified from the ...
  • Gut microbiome-immune interactions and their role in rheumatoid arthritis development 
    Nurgaziyev, Madiyar; Issilbayeva, Argul; Bersimbaev, Rakhmetkazhi; Ilderbayev, Oralbek; Vinogradova, Elizaveta; Jarmukhanov, Zharkyn; Nurgozhina, Ayaulym; Sergazy, Shynggys; Kozhabergen, Nuray; Akhmetova, Zhanar; Meiramova, Assel; Chulenbayeva, Laura; Ibrayeva, Aigerim; Mukhanbetzhanov, Nurislam; Mukhanbetzhanova, Zhanel; Kozhakhmetov, Samat; Ainabekova, Bayan; Kushugulova, Almagul (PeerJ, 2024)
    Objective: The primary objective is to study the impact of gut microbiota and their interactions with diverse immunological markers on the development of rheumatoid arthritis. Methods: This study was performed in Astana, ...
  • Isolation of Bacillus sp. A5.3 Strain with Keratinolytic Activity 
    Aktayeva, Saniya; Baltin, Kairat; Kiribayeva, Assel; Akishev, Zhiger; Silayev, Dmitriy; Ramankulov, Yerlan; Khassenov, Bekbolat (Biology, 2022)
    Environmental safety and economic factors necessitate a search for new ways of processing poultry farm feathers, which are 90% β-keratin and can be used as a cheap source of amino acids and peptones. In this study, ...
  • Isolation and Characterization of Bacteria with High Electroactive Potential from Poultry Wastewater 
    Temirbekova, Aliya; Tekebayeva, Zhanar; Temirkhanov, Aslan; Yevneyeva, Dinara; Sadykov, Azamat; Meiramkulova, Kulyash; Mkilima, Timoth; Abzhalelov, Akhan (Biology, 2023)
    Natural resources are in short supply, and the ecosystem is being damaged as a result of the overuse of fossil fuels. The creation of novel technology is greatly desired for investigating renewable and sustainable energy ...
  • Fermentation Conditions of Lactobacilli for the Production of Lactose-Free Starter Culture 
    Imanbayeva, Madina; Masalimov, Zhaksylyk; Prosekov, Alexander Yurievich; Milentyeva, Irina Sergeevna; Sagyndykov, Utemurat Zulhanaevich (OnLine Journal of Biological Sciences, 2024-01)
    This research aims to determine the fermentation conditions and viability in a medium simulating the gastrointestinal tract and to examine the antagonistic potential of Lactobacillus acidophilus (Lb. acidophilus) and ...
  • Effective photochemical treatment of a municipal solid waste landfill leachate 
    Makhatova, Ardak; Mazhit, Birzhan; Sarbassov, Yerbol; Meiramkulova, Kulyash; Inglezakis, Vassilis J.; Poulopoulos, Stavros G. (PLOS ONE, 2020-09)
    This work aimed at studying the photochemical treatment of a landfill leachate using ultraviolet light, hydrogen peroxide, and ferrous or ferric ions, in a batch recycle photoreactor. The effect of inorganic carbon presence, ...
  • Biofilm-Enhanced Natural Zeolite Material in Purification Performance for Slaughterhouse Wastewater 
    Mkilima, Timoth; Meiramkulova, Kulyash; Kydyrbekova, Aliya; Bazarbayeva, Tursynkul; Daldabayeva, Gulnur; Zholdasbek, Aknur; Shegenbayev, Abzal; Dzhexenbayev, Nurbolat; Oshanova, Gulaina; Kaisagaliyeva, Gulzhakhan (Water, 2023-10)
    This study focuses on evaluating the efficacy of biofilm-enhanced natural zeolite for the purification of slaughterhouse wastewater. The investigation encompasses four distinct treatment methods: employing natural zeolite ...

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